Brian P Kavanagh Selected Research

Hypercapnia

1/2017	α-Tocopherol transfer protein mediates protective hypercapnia in murine ventilator-induced lung injury.
2/2015	Hypercapnia: clinical relevance and mechanisms of action.
10/2014	Hypercapnia attenuates ventilator-induced lung injury via a disintegrin and metalloprotease-17.
6/2012	Sustained therapeutic hypercapnia attenuates pulmonary arterial Rho-kinase activity and ameliorates chronic hypoxic pulmonary hypertension in juvenile rats.
5/2010	Hypercapnic acidosis in ventilator-induced lung injury.
1/2010	Bench-to-bedside review: carbon dioxide.
11/2009	Therapeutic effects of hypercapnia on chronic lung injury and vascular remodeling in neonatal rats.
11/2006	Therapeutic hypercapnia prevents chronic hypoxia-induced pulmonary hypertension in the newborn rat.
3/2004	Permissive hypercapnia--role in protective lung ventilatory strategies.
1/2004	Therapeutic hypercapnia is not protective in the in vivo surfactant-depleted rabbit lung.

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Brian P Kavanagh Research Topics

Disease

33	Lung Injury 01/2022 - 11/2003
13	Hypercapnia 01/2017 - 11/2003
12	Ventilator-Induced Lung Injury 01/2018 - 01/2004
9	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2021 - 07/2014
7	Pulmonary Hypertension 02/2015 - 09/2005
7	Pulmonary Atelectasis 02/2013 - 04/2005
6	Sepsis (Septicemia) 03/2021 - 10/2005
6	Hypoxia (Hypoxemia) 06/2012 - 09/2005
5	Inflammation (Inflammations) 01/2018 - 04/2011
5	Critical Illness (Critically Ill) 11/2015 - 07/2005
4	Acidosis 01/2018 - 02/2006
4	Acute Lung Injury 04/2017 - 07/2007
4	Heart Arrest (Cardiac Arrest) 06/2014 - 02/2006
4	Pain (Aches) 03/2011 - 01/2007
4	Hypocapnia 05/2010 - 11/2003
4	Vascular Remodeling 11/2009 - 11/2006
3	Edema (Dropsy) 01/2019 - 06/2008
2	Atrophy 01/2018 - 11/2015
2	Infections 02/2015 - 08/2014
2	Pneumonia (Pneumonitis) 08/2014 - 06/2010
2	Lung Diseases (Lung Disease) 08/2014 - 06/2010
2	Right Ventricular Hypertrophy 06/2012 - 12/2010
2	Delirium 08/2010 - 01/2007
2	Coma (Comas) 08/2010 - 01/2007
2	Hyperventilation 05/2010 - 11/2003
2	Alkalosis 05/2010 - 11/2003
2	Hypertension (High Blood Pressure) 01/2007 - 02/2006
2	Asphyxia (Suffocation) 02/2006 - 02/2006
1	Peritonitis 01/2020
1	Pulmonary Edema 01/2018
1	Paralysis (Palsy) 01/2016
1	Brain Ischemia (Cerebral Ischemia) 02/2015
1	Cystic Fibrosis (Mucoviscidosis) 08/2014
1	Pseudomonas Infections 08/2014
1	Genetic Predisposition to Disease (Genetic Predisposition) 02/2012
1	Tetralogy of Fallot (Fallot Tetralogy) 12/2011
1	Bronchopulmonary Dysplasia 02/2011

Drug/Important Bio-Agent (IBA)

11	CytokinesIBA 01/2018 - 01/2004
8	Surface-Active Agents (Surfactants)IBA 01/2022 - 11/2003
6	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2004
6	Carbon DioxideIBA 02/2015 - 11/2003
5	Oxygen (Dioxygen)IBA 01/2018 - 11/2003
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2013 - 01/2004
4	rho-Associated KinasesIBA 06/2012 - 02/2008
4	EicosanoidsIBA 04/2011 - 09/2005
4	Messenger RNA (mRNA)IBA 05/2010 - 03/2004
3	Interleukin-6 (Interleukin 6)IBA 01/2018 - 04/2011
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2013 - 01/2007
3	ProstaglandinsIBA 04/2011 - 05/2010
3	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 04/2011 - 05/2010
3	Y 27632IBA 12/2010 - 02/2008
2	LigandsIBA 01/2018 - 10/2014
2	AntioxidantsIBA 01/2017 - 11/2006
2	LipidsIBA 01/2017 - 04/2011
2	Anesthetics (Anesthetic Agents)IBA 08/2015 - 11/2010
2	LipopolysaccharidesIBA 04/2015 - 10/2005
2	Epinephrine (Adrenaline)FDA LinkGeneric 06/2014 - 02/2006
2	ChemokinesIBA 01/2013 - 05/2010
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 06/2012 - 02/2008
2	Propofol (Diprivan)FDA LinkGeneric 03/2011 - 11/2010
2	Hypnotics and Sedatives (Sedatives)IBA 08/2010 - 01/2007
2	Analgesics (Analgesic Drugs)IBA 08/2010 - 01/2007
2	Pharmaceutical PreparationsIBA 05/2010 - 07/2005
2	Tyrosine (L-Tyrosine)FDA Link 05/2010 - 11/2009
2	8-epi-prostaglandin F2alphaIBA 11/2006 - 03/2005
1	Meropenem (Merrem)FDA LinkGeneric 03/2021
1	Heme Oxygenase-1IBA 01/2020
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2018
1	AcidsIBA 11/2017
1	Superoxides (Superoxide)IBA 01/2017
1	Tocopherols (Tocopherol)IBA 01/2017
1	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 01/2017
1	Histones (Histone)IBA 04/2015
1	DNA (Deoxyribonucleic Acid)IBA 04/2015
1	Deoxyribonucleases (DNase)FDA Link 04/2015
1	Metalloproteases (Metalloproteinases)IBA 10/2014
1	DisintegrinsIBA 10/2014
1	Protein Kinases (Protein Kinase)IBA 10/2014
1	ArginaseIBA 08/2014
1	Vasopressins (Vasopressin)IBA 06/2014
1	NitrogenIBA 08/2013
1	Guanosine Monophosphate (5' Guanylic Acid)IBA 06/2012
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 06/2012
1	SphingolipidsIBA 04/2011
1	CeramidesIBA 04/2011
1	Ibuprofen (Motrin)FDA LinkGeneric 01/2011

Therapy/Procedure

20	Artificial Respiration (Mechanical Ventilation) 01/2019 - 02/2006
13	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 01/2021 - 11/2003
11	Mechanical Ventilators (Ventilator) 11/2018 - 11/2003
6	Therapeutics 03/2021 - 02/2008
2	Extracorporeal Membrane Oxygenation 01/2018 - 11/2002
2	Critical Care (Surgical Intensive Care) 02/2012 - 01/2007
2	Continuous Positive Airway Pressure 12/2011 - 10/2005
2	Analgesia 11/2010 - 08/2010
2	Length of Stay 08/2010 - 01/2007
2	Cardiopulmonary Resuscitation (CPR) 10/2009 - 02/2006
1	Transplantation 03/2021
1	Fontan Procedure (Fontan Operation) 12/2011
1	Right Heart Bypass (Cavopulmonary Anastomosis) 12/2011
1	Subcutaneous Injections 12/2010